Evaluation the effect of Plasma Rich Platelet gel on the rate of Donor site wound healing in burn patients

Title: Evaluation the effect of Plasma Rich Platelet gel on the rate of donor site wound healing in burn patients. Background: Platelet-rich plasma (PRP) is a product derived from human blood that due to the large growth factors, many applications in various medical fields. Objective: The purpose of this triple blind clinical trial to investigate the effect of platelet-rich plasma gel on the rate of wound healing in burn patients is the removal of skin grafts for transplantation. Method: 33 patients with degree burns IIb and III (mean age 33 years) who were referred to the clinic Vasei hospital burn unit were selected. In each patient the graft harvest site for a skin graft was divided into two parts. In one area of the gel was applied topically and then standard dressing was used and only standard dreesing was used in another area. On the 10th and 30th accelerate healing, by two experts on the consequences of the wound epithelialization and granulation, pigmentation and surface vascularity was evaluated macroscopically. Results: The rate of wound healing at the site of harvest skin grafts for transplantation in the intervention group than the control group, according to both specialists who were taken individually, was more (P = 0.001). Conclusion: These results indicate that the rate of wound healing on the donor site if the use of PRP dramatically increased. Keywords: Burn, Platelet-rich plasma, Graft, Skin, Wound healin

Clustering sustainable suppliers in the plastics industry: A fuzzy equivalence relation approach

Nowadays, pure economic supply chain management is not commonly contemplated among companies (especially buyers), as recently novel dimensions of supply chains, e.g., environmental, sustainability, and risk, play significant roles. In addition, since companies prefer buying their needs from a group of suppliers, the problem of supplier selection is not solely choosing or qualifying a supplier from among others. Buyers, hence, commonly assemble a portfolio of suppliers by looking at the multi-dimensional pre-determined selection criteria. Since sustainable supplier selection criteria are often assessed by linguistic terms, an appropriate clustering approach is required. This paper presents an innovative way to implement fuzzy equivalence relation to clustering sustainable suppliers through developing a comprehensive taxonomy of sustainable supplier selection criteria, including supply chain risk. Fifteen experts participated in this study to evaluate 20 suppliers and cluster them in the plastics industry. Findings reveal that the best partitioning occurs when the suppliers are divided into two clusters, with 4 (20%) and 16 (80%) suppliers, respectively. The four suppliers in cluster one are performing better in terms of the capability of supplier/delivery, service, risk, and sustainability criteria such as environment protection/management, and green innovation. These factors are critical in clustering and selecting sustainable suppliers. The originality of this study lies in developing an all-inclusive set of criteria for clustering sustainable suppliers and adding risk factors to the conventional supplier selection criteria. In addition to partitioning the suppliers and determining the best-performing ones, this study also highlights the most influential factors by analysing the suppliers in the best cluster

Comparison of Melatonin Profile and Alertness of Firefighters with Different Work Schedules

Introduction: A two-shift work schedule with different rotations is common among firefighters in Iranian petrochemical companies. This study compared salivary melatonin and sleepiness on the last night before turning to day shift at 19:00, 23:00, 3:00, and 7:00 among petrochemical firefighters (PFFs) working seven and four consecutive night shifts. Methods: Sixty four PFFs working in the petrochemical industry were selected. To measure melatonin, saliva samples were taken, whereas the KSS index was used to assess sleepiness. Chi-square and independent samples t-test were carried out to analyze the data, and generalized linear model (GLM) was employed to determine the effect of confounding factors such as lighting and caffeine. Results: The levels of melatonin at 3:00 and 7:00, and the overall changes during the shift in the two shift patterns under the study were different (P < 0.05). Sleepiness was significantly different only at 3:00 in the two studied shift patterns, while the effects of lighting and caffeine on melatonin changes were not significant (P > 0.05). Conclusion: It seems that a slow shift rotation is better because it reduces the secretion of melatonin (hence reducing sleepiness during the night) and changes the peak of melatonin secretion to the daytime, which is a sign of adaptation

The relationship between mental workload and general health among welders of Tehran Heavy Structure Metal Company

Mental workload is one of the factors that influence individuals’ performance in the work environment as well as their efficiency and productivity. The present study aimed at examining the association between mental workload and general health among welders of Tehran Heavy Structuress Metal Company.This cross-sectional study was conducted in 2016. The sample included 100 welders who were working in Tehran Heavy Structures Metal Company. Sampling was done through conducting a census. A demographic questionnaire, General Health Questionnaire-28 (GHQ-28), and National Aeronautics and Space Administration Task Load Index (NASA-TLX) mental workload questionnaire were used to collect data. The obtained data were fed into SPSS (version 22) and analyzed through Chi-square, one-way ANOVA, Kruscal Wallis Test, Pearson product moment correlation, and Mann-Whitney U Test.The results showed that the participating welders had an average age of 36.16±7.81, an average work experience of 9.65±5.83, and a BMI of 25.95±3.39 kg/m2. The mean and standard deviation of the overall score of welders’ mental workload were 65.88±21.15. The cut-off scores for the total mental workload questionnaire and the subscales were respectively set at 23 and 6. The results demonstrated that 26% of the welders were suspected of mental disorder. Furthermore, the results of Pearson correlation indicated that there was no significant relationship between the overall score of NASA mental workload and that of general health (p-value>0.05).Welders’ mental workload is relatively high. Therefore, further research should be conducted in order to identify main risk factors that lead to mental and health disorder. Future studies should also be performed to present some solutions for te purpose of decreasing or preventing these side effects among welders as much as possible.

Beyond the outbreak of COVID-19: factors affecting burnout in nurses in Iran

Background: Nurses working in treating patients with COVID-19 are exposed to various stressors, such as fear of COVID-19, stress, and high workload, leading to burnout. Objectives: This study aimed to identify the level of burnout and its predictors in nurses working in hospitals for COVID-19 patients. Methods: Participants in this study were nurses working in 11 hospitals for COVID-19 patients in the Fars province of Iran. The Maslach burnout and the UK Health and Safety stress questionnaires were used to assess burnout and stress, respectively. Analysis, using multiple regression in the SPSS21 software, aimed to identify the factors affecting burnout. Findings: The mean level of burnout in the nurses at the COVID-19 hospitals was 57 out of 120, and burnout was affected by workload (β = 0.69, p < 0.001), job stress (β = 0.25, p < 0.001) and inadequate hospital resources for the prevention of COVID-19 (β = –0.16, p < 0.001). These three variables explained 87% of the variance in burnout. Conclusions: The burnout of nurses directly exposed to COVID-19 patients is more than nurses in other wards, and workload is the most significant cause of burnout in them. Therefore, necessary measures such as hiring more nurses, reducing working hours and increasing rest periods are necessary to reduce workload. In addition, the job stress of these nurses should be managed and controlled, and the hospital resources needed to prevent this disease should be provided

Investigation of Workers’ Sleep Quality in GoleGohar Mineral Industries Co., Sirjan

Sleeping is an important physiological process, wielding deep effect on the spiritual and physical health of individuals. The present study has been carried out to investigate workers’ sleep quality in GoleGohar Mineral Industries Co., Sirjan, Iran. This cross-sectional and descriptive-analytical study has been carried out in 2012. The statistical society included 345 workers in of psychological health of workers in Hematite and Pelletizing section in GoleGohar Mineral Industries Co., Sirjan. The sampling method was simple random selection. Pittsburg Sleep Quality Index (PSQI) was applied in the study, with the Cronbach validity of 0.83.  Analysis of data was carried out under SPSS 19 software using descriptive and inferential statistics tests. Workers averaged 30.92±4.78 years of age and their working experience averaged 5.47±3.24 years. 82.9 percent of the workers responding to the questionnaire were satisfied with their jobs, and 17.1 percent were not satisfied. Body Mass Index (BMI) for workers averaged 24.5±3.51 Kg/m3.51 Kg/m2 46.9 percent of workers experienced satisfactory sleep and 53.1 percent of them experienced unsatisfactory sleep. The present study has reported workers’ sleep quality in a modest level. With high influence of sleep quality on individual performance and on their general health, and high incidence of workplace events, this aspect of workers’ health should be in the focus of policy-makers and relevant authorities in health sector

The relationship between mental workload and general health among welders of Tehran Heavy Structures Metal Company

Mental workload is one of the factors that influence individuals’ performance in the work environment as well as their efficiency and productivity. The present study aimed at examining the association between mental workload and general health among welders of Tehran Heavy Structuress Metal Company.This cross-sectional study was conducted in 2016. The sample included 100 welders who were working in Tehran Heavy Structures Metal Company. Sampling was done through conducting a census. A demographic questionnaire, General Health Questionnaire-28 (GHQ-28), and National Aeronautics and Space Administration Task Load Index (NASA-TLX) mental workload questionnaire were used to collect data. The obtained data were fed into SPSS (version 22) and analyzed through Chi-square, one-way ANOVA, Kruscal Wallis Test, Pearson product moment correlation, and Mann-Whitney U Test.The results showed that the participating welders had an average age of 36.16±7.81, an average work experience of 9.65±5.83, and a BMI of 25.95±3.39 kg/m2. The mean and standard deviation of the overall score of welders’ mental workload were 65.88±21.15. The cut-off scores for the total mental workload questionnaire and the subscales were respectively set at 23 and 6. The results demonstrated that 26% of the welders were suspected of mental disorder. Furthermore, the results of Pearson correlation indicated that there was no significant relationship between the overall score of NASA mental workload and that of general health (p-value>0.05).Welders’ mental workload is relatively high. Therefore, further research should be conducted in order to identify main risk factors that lead to mental and health disorder. Future studies should also be performed to present some solutions for te purpose of decreasing or preventing these side effects among welders as much as possible

A brief review on DNA vaccines in the era of COVID-19

This article provides a brief overview of DNA vaccines. First, the basic DNA vaccine design strategies are described, then specific issues related to the industrial production of DNA vaccines are discussed, including the production and purification of DNA products such as plasmid DNA, minicircle DNA, minimalistic, immunologically defined gene expression (MIDGE) and Doggybone (TM). The use of adjuvants to enhance the immunogenicity of DNA vaccines is then discussed. In addition, different delivery routes and several physical and chemical methods to increase the efficacy of DNA delivery into cells are explained. Recent preclinical and clinical trials of DNA vaccines for COVID-19 are then summarized. Lastly, the advantages and obstacles of DNA vaccines are discussed